The exact mechanism that allows Zoloft to combat depression, Synthroid 100 mcg anxiety and OCD is still not completely understood, however what researchers have noticed is that Zoloft affects simply click the following article way serotonin is managed by the human body. Serotonin is part of a drug family known as selective serotonin re-uptake inhibitors (or SSRI's). SSRI's increase the level of serotonin in the brain by inhibiting (not preventing) its breakdown. And yes, while this may seem complicated it really isn't.